Opioids act on the gastrointestinal system to decrease gastric, duodenal, and large intestinal motility which can lead to delayed gastric emptying and induce an ileus (Murray 1984). The secretion of pancreatic, biliary, intestinal, and gastric secretions can be delayed, causing a stoppage in food digestion. With opioid administration, patients can develop a constriction of the sphincter of Oddi and an increased common bile duct pressure (Gustein and Akil 2001). Constipation is an extremely common problem with the use of opioids.
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Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.