Methylprednisolone Acetate Depo Medrol

Depo- MedrolĀ®R (Pfizer, New York, NY) is a high-potency steroid with high glucocorticoid effects and low mineralocorticoid effects. The preparation when injected provides for a slow release of the active steroid to the target site. Controversy occurred over its use in epidu-ral steroid injections with respect to the occurrence of arrachnoiditis and other neurologic injuries when it was accidentally injected intrathecally (Bernat et al. 1976). However, there are other studies of deliberate intrathecal injection of Depo- MedrolĀ®R without neurotoxicity (Kotani et al. 2000).

What is clear however is that there is a potential for intravascular injection with the use of any particulate steroid which can lead to arteriole occlusion and stroke. Cervical trans-foraminal epidural steroid injections, for example, are now discouraged (Rathmell et al. 2000, Cousins 2000).

Was this article helpful?

0 0
10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment