Psychostimulants

Agents which are used in patients with attention deficit disorder, parkinsonism, narcolepsy, workshift sedation, and treatment-resistant depression to augment antidepressants, to counter iatrogenic sedation from opioids and other adjunctive medications, and to treat fatigue or sedation in terminal illness. The majority of psychostimulants are amphetamine based and can cause dopamine release in increasing doses, which can result in behavioral changes. Care must be taken with these drugs since significant abuse potential can occur.

Dextroamphetamine (Dexedrine®): 5-60 mg/day Methylphenidate (Ritalin®®): 10-30 mg/day Magnesium pemoline (Cylert®): 37.5-112.5 mg/day

Amphetamine/Dextroamphetamine (Adderall®®): Extended release action; 1040 mg/day, used for adult attention deficit disorder if patient had favorable response to Ritalin®R .

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