Epinephrine and Norepinephrine

Biological interest in catecholamines, in particular epinephrine, dates back to the final years of the nineteenth-century. Within one decade after Oliver and Schaefer in 1895 showed that an extract of the adrenal medulla produced a marked increase in blood pressure, its active constituent epinephrine (adrenaline) was isolated, purified, and synthesized. Epinephrine was the first hormone isolated in crystalline form. Elliott's studies in 1905 with epinephrine are of greater importance from our...