Similar to retinoic acid, the vitamin D receptor (VDR) is a member of the steroid/thyroid hormone superfamily of receptors. These act as ligand-dependent transcription factors that regulate gene expression. In intestine, bone, kidney, and other tissues, calcitriol binds to VDR localized in the cytoplasm, and the complex forms a heterodimer with a retinoid RXR. RXRs are also involved in vitamin A action and the reader is referred to that section for more information. This complex translocates to the nucleus and binds to vitamin D response elements (VDREs) associated with the promoter region of target genes and, together with coactivators, regulates target gene transcription. Over 50 genes have been identified that are controlled by calcitriol.

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Using Exercise To Get Rid Of Man Boobs

Using Exercise To Get Rid Of Man Boobs

In this guide, youll learn just what kinds of exercises you can use to get rid of man boobs forever. It includes two different types of exercises those designed to burn body fat, helping you lose excess weight all over your body and targeted chest exercises which will shrink your man boobs until you have a masculine, sexy chest.

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