Hypervitaminosis

Niacin, in doses that range above the DRI but below that required for dyslipidemias, is unlikely to produce adverse effects. However, adverse effects of niacin are seen when this vitamin is used at pharmacological doses above 1 g/day in the treatment of dyslipidemia. Notable adverse effects include flushing because of vasodilation; dermatological effects including dry skin, pruritus and hyperkeratosis; gastrointestinal effects including peptic ulcer, stomach pain, nausea, and diarrhea; elevations in serum uric acid and glucose (in Type 2 diabetics); and rare hepatotoxic-ity.159-161 Traditionally, hepatotoxicity has been more associated with the sustained release as compared to the immediate release formulations; however, recent analysis of niacin-ER adverse events suggests the opposite may be true for this formulation.162

Of particular note is that niacinamide, even in high doses, is not effective in hyperlipdemias and only rarely produces the vascular, dermatological and hepatotoxicity associated with high doses of niacin. Even gastrointestinal upset is less common with niacinamide. For this reason, niacinamide would be the preferred form for vitamin supplementation, especially if taken in high doses.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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