I I

Ser Arg Tyr

Met Arg Pro

5g!u Lys Asn25

Phe Gly Ala

Arg Val g!u

Tyr Pro Asp

Corticotropin

Cosyntropin. Cosyntropin (Cortrosyn) is a synthetic peptide containing the first 24 amino acids of natural corticotropin. Cosyntropin is used as a diagnostic agent to test for adrenal cortical deficiency. Plasma hydrocortisone concentration is determined before and 30 minutes after the administration of 250 fig of cosyntropin. Most normal re

Phe g!u

Phe35

Ala g!u aL

TABLE 27.4 Pharmaceutical^ Important Adrenocorticotropic Hormone Products

Preparation

Proprietary Usual Adult Usual Dose Usual Pediatric

Name Category Dosea Rangea Dosea

TABLE 27.4 Pharmaceutical^ Important Adrenocorticotropic Hormone Products

Preparation

Proprietary Usual Adult Usual Dose Usual Pediatric

Name Category Dosea Rangea Dosea

Corticotropin

Adrenocorticotropic

Adrenocorticotropic hormone:

Adrenocorticotropic

Parenteral,

injection,

hormone;

parenteral, 20 USP units, q.i.d.

hormone:

0.4 U/kg of

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