Info
- VCH_
Figure 20.9 • Repaglinide solution ionization. The proton dissociation microconstants combine to account for the observed macro pKa values, as well as the lipid/aqueous phase partitioning characteristics.12
TABLE 20.4 Glinides Marketed in the United States3
Protein Volume of Lipid Partitioning Biotrans- Oral Bio- Dosage Forms
Drug Binding Distribution Character formation availability Elimination and Dose Range
TABLE 20.4 Glinides Marketed in the United States3
Protein Volume of Lipid Partitioning Biotrans- Oral Bio- Dosage Forms
Drug Binding Distribution Character formation availability Elimination and Dose Range
|
Repaglinide |
98%, Vss = 31 L |
Log D7.4 ~2.6c |
Extensive 56%d |
8% urine as |
Tablets |
|
Was this article helpful?  Conquering Fear In The 21th CenturyThe Ultimate Guide To Overcoming Fear And Getting Breakthroughs. Fear is without doubt among the strongest and most influential emotional responses we have, and it may act as both a protective and destructive force depending upon the situation. |
Post a comment