Info

Granulocyte colony-stimulating factor

Neutrophil production

Macrophage colony-stimulating factor

Macrophage production

Stem cell factor

Controls activity through myeloid branch

Figure 4.12 • Cytokine-mediated cascade leading to different blood cell types. (EPO, erythropoietin; G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-X, interleukins; M-CSF, macrophage colony-stimulating factor; SCF, stem cell factor; TPO, thrombopoietin.)

Figure 4.12 • Cytokine-mediated cascade leading to different blood cell types. (EPO, erythropoietin; G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-X, interleukins; M-CSF, macrophage colony-stimulating factor; SCF, stem cell factor; TPO, thrombopoietin.)

progenitor and one quiescent. The active precursor matures to give hematopoietic progenitors and then circulating blood cells. The quiescent stem cells rejoin the stem cell pool. Hence, the number of parental cells is always the same. This process is termed self-renewal.

Was this article helpful?

0 0
Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

Get My Free Ebook


Post a comment