It was thought originally that cholecystokinin and pancreozymin were two different hormones. Cholecystokinin was thought to be responsible for contraction of the gallbladder, whereas pancreozymin was believed to induce secretion of pancreatic enzymes. It is now clear that both actions are caused by a single 33-residue polypeptide, referred to as cholecystokinin-pancreozymin (CCK-PZ). CCK-PZ is secreted in the blood in response to the presence of food in the duodenum, especially long-chain fatty acids. The five COOH-terminal amino acid residues are identical with those in gastrin. The COOH-terminal octapeptide retains full activity of the parent hormone.




Was this article helpful?

0 0
Conquering Fear In The 21th Century

Conquering Fear In The 21th Century

The Ultimate Guide To Overcoming Fear And Getting Breakthroughs. Fear is without doubt among the strongest and most influential emotional responses we have, and it may act as both a protective and destructive force depending upon the situation.

Get My Free Ebook

Post a comment