O

Alfentanil Remifentanil

Figure 24.9 • 4-Phenylpiperidines and 4-anilidopiperidines.

renal dysfunction, thus cannot eliminate the normeperidine, and those on CYP inducers.81

In addition to the CNS toxicity of normeperidine, meperi-dine has also been found to be a weak serotonin reuptake inhibitor and has been involved in serotonin toxicity reactions when used with monoamine oxidase inhibitors or serotonin reuptake inhibitors.82 Meperidine is available in tablet, liquid, and injectable forms. The use of meperidine should be limited to those patients that have true allergies to the morphine-type opioids, and patients should be monitored for toxicity.

Was this article helpful?

0 0
How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

Get My Free Ebook


Post a comment