For renal imaging and GFR studies, the patient receives an intravenous injection of 3 to 5 mCi (111-185 MBq) and the kidneys are imaged for 20 to 30 minutes. The GFR is calculated by a quantitative method using a combination of imaging and counting the radioactivity in serum and urine samples. Renal and brain perfusion studies use doses from 10 to 20 mCi (370-740 MBq). Both dynamic and static images are usually acquired for perfusion studies. For lung studies, 30 to 50 mCi (1.11-1.85 GBq) is placed in a closed, disposable nebulizer system. After 5 to 10 minutes of inhalation by the patient, the nebulizer is detached and patient images from various projections are obtained. Images are comparable to those obtained with xenon-133.
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