O Mechanisms Of Action Of Anticonvulsants

At the cellular level, three basic mechanisms are believed to contribute to the antiepileptic action of the currently marketed anticonvulsants.18,19 These are (a) modulation of voltage-gated ion channels (Na+, Ca2+, and K+), (b) enhancement of y-aminobutyric acid (GABA)-mediated inhibitory neurotransmission, and (c) attenuation of excitatory (particularly glutamate-mediated) neurotransmission in the brain. Many of AEDs, especially the newer drugs, work by more than one of the above mechanisms of actions, therefore possessing a broader spectrum of antiepilep-tic action.

Voltage-Gated Ion Channels as Targets for Anticonvulsants

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How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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