O Mechanisms Of Action Of Anticonvulsants

At the cellular level, three basic mechanisms are believed to contribute to the antiepileptic action of the currently marketed anticonvulsants.18,19 These are (a) modulation of voltage-gated ion channels (Na+, Ca2+, and K+), (b) enhancement of y-aminobutyric acid (GABA)-mediated inhibitory neurotransmission, and (c) attenuation of excitatory (particularly glutamate-mediated) neurotransmission in the brain. Many of AEDs, especially the newer drugs, work by more than one of the above mechanisms of actions, therefore possessing a broader spectrum of antiepilep-tic action.

Voltage-Gated Ion Channels as Targets for Anticonvulsants

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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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