Oh

(18F)-2-Fluoro-2-deoxy-D-glucose

Gallium Radiochemistry

The only radioisotope of gallium that is presently used is gallium-67, which is produced in a cyclotron by proton bombardment of a zinc metal target according to the 68Zn(p,2n)67Ga nuclear reaction. Gallium-67 (ix/2 = 78.2 hours) decays by EC to stable zinc-67 with principal y-ray emissions of 93 keV (38%), 185 keV (24%), and 300 keV (16%). The radiotracer is isolated by dissolution of the target in hydrochloric acid followed by isopropyl ether extraction of the gallium-67 from the zinc and other impurities. Gallium-67 is back-extracted from the isopropyl ether into 0.2 M hydrochloric acid, evaporated to dryness, and dissolved in sterile, pyrogen-free 0.05 M hydrochloric acid.7 Gallium is an amphoteric element that acts as a metal at low pH but forms insoluble hydroxides when the pH is raised above 2 in the absence of chelating agents. At high pH, gallium hydroxide acts as a nonmetal and dissolves in ammonia to form gallates. Gallium forms compounds of oxidation states +1, +2, and +3; however, only the Ga+3 state is stable in aqueous solutions.

Was this article helpful?

0 0
How To Bolster Your Immune System

How To Bolster Your Immune System

All Natural Immune Boosters Proven To Fight Infection, Disease And More. Discover A Natural, Safe Effective Way To Boost Your Immune System Using Ingredients From Your Kitchen Cupboard. The only common sense, no holds barred guide to hit the market today no gimmicks, no pills, just old fashioned common sense remedies to cure colds, influenza, viral infections and more.

Get My Free Audio Book


Post a comment