Ambrisentan. Ambrisentan, (+)-(2S)-2-[(4,6-dimethyl-pyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid (Letairis), is a potent ETA selective endothelin antagonist that, is indicated, in the treatment of pulmonary arterial hyperten sion (PAH). PAH is a rare disease that if left untreated has a high mortality rate. In June of 2007, the FDA granted approval of ambrisentan for once-daily treatment of PAH. Studies have shown that it improves a 6-minute walk by about 30 to 60 m for patients receiving placebo.49

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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