Enalapril Maleate. Enalapril maleate, 1-[n[(s)-1-car-boxy-3-phenylpropyl]-l-alanyl]-l-proline 1'-ethyl ester maleate (Vasotec), is a long-acting ACE inhibitor. It requires activation by hydrolysis of its ethyl ester to form the diacid enalaprilat. Enalapril is devoid of the side effects of rash and loss of taste seen with captopril. These side effects are similar to those of the mercapto-containing drug penicillamine. The absence of the thiol group in enalapril maleate may free it from these side effects. The half-life is 11 hours.
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