The Hydroxylgroup

Although not requisite for activity, a suitably placed alcoholic hydroxyl group enhances antimuscarinic activity over that of a similar compound without the hydroxyl group. The position of the hydroxyl group relative to the nitrogen appears to be fairly critical, with the diameter of the receptive area estimated to be about 2 to 3 A. It is assumed that the hy-droxyl group contributes to the strength of binding, probably by hydrogen bonding to an electron-rich portion of the receptor surface.

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How To Reduce Acne Scarring

How To Reduce Acne Scarring

Acne is a name that is famous in its own right, but for all of the wrong reasons. Most teenagers know, and dread, the very word, as it so prevalently wrecks havoc on their faces throughout their adolescent years.

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