Figure 12.2 • Metabolism of benzodiazepines and their duration of action.
lized by cytochrome P450 (CYP) 3A4 and CYP2C19. CYP3A4 inhibitors (erythromycin, clarithromycin, ritonavir, itraconazole, ketoconazole, nefazodone, and grapefruit juice) can affect their metabolism. However, they do not induce the metabolism of other drugs. Therefore, the drugs have fewer drug interactions than barbiturates. In addition, they have lower abuse potential and a much greater margin of safety than the barbiturates.
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What exactly is a detox routine? Basically a detox routine is an all-natural method of cleansing yourbr body by giving it the time and conditions it needs to rebuild and heal from the damages of daily life and the foods you eat and other substances you intake. There are many different types of known detox routines.