Fho

CHj — CHa- CHj— N H - R10 CH2 - CH2~ CH2~ N N — Rio

Rio = -CH3 ( trifluoperazine ) / -CH2CH2OH ( fluphenazine )

Figure 6. Proposed degradation pathways for trifluoperazine and fluphenazine.

Table 5 Relative intensities as a % of the dégradants from trifluoperazine and fluphenazine

Phenothiazine Dégradant 30W UV Sunlight Fluorescent/

Derivative (254nm) diffuse light

Trifluoperazine/Fluphenazine 17 1.37/34.67 3.92/2.04 0.10/3.35

Table 6 Relative intensities as a % of sulphoxides

Phenothiazine Derivative

30WUV (254nm)

Sunlight

Fluorescent/ diffuse light

Prochlorperazine

0 0

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