Oh

CL_Cl HO_CI

Cl OH Cl ci

Cl OH

Cl OH

2.6.3 fi-Lactam Antibiotics. In compounds containing an oxime function such as aztreonam (195)195 and cefotaxime (196),196 syn-anti isomerisation occurs rapidly upon irradiation (thus diminishing the pharmacological activity), and is accompanied by degradation processes.

CONH Me

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