Photoprotection Systems

The design of a photoprotective system presents the double advantage of reducing the phototoxic effect of the drug and, in the meantime, of shedding more light on the molecular mechanism of photosensitization.

5.1 Inorganic Ions and their Complexes

The inorganic ions Cu11, Mn11, Co11, are able to reduce the photoinduced damage. These ions protect only within a range of concentrations, since for higher amounts toxic effects are observed. These species can act by redox scavenging of the photogenerated drug and biomacromolecule radicals,68'69 which are the main responsible species for the biological

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