We would like to dedicate this volume to Prof. David Grant, who passed away on December 9, 2005. Prof. Grant held the William and Mildred Peters Endowed Chair in the College of Pharmacy, Department of Pharmaceutics at the University of Minnesota. Prof. Grant was an internationally recognized authority on solid-state properties of drugs. His research directly impacted the ability to make safe and effective pharmaceutical agents with reproducible and predictable bio-pharmaceutical performance. Prof. Grant was a prolific scientist with more than 200 scientific articles to his credit. He also gave back to the scientific community in many ways, including his participation on the editorial boards of various scientific publications including the Journal of Pharmaceutical Sciences, where he served as Associate Editor, as well as Pharmaceutical Development and Technology and The AAPS Journal (formerly AAPS Pharm Sci). Prof. Grant was often singled out by his peers for his excellent contributions to science; he received such awards as the Pharmaceutics Award in Excellence from the Pharmaceutical Research and Manufacturers Association Foundation as well as the 2004 Dale E. Wurster Research Award, the highest recognition in his discipline from the American Association of Pharmaceutical Scientists (AAPS). The legacy left by Prof. Grant is substantial and transformational. We are indebted to him on so many levels, including his contribution to this monograph.

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