Atypical Antipsychotic Drugs Synonyms

Second- and third-generation antipsychotics Definition

All conventional antipsychotics (also called firstgeneration antipsychotics) share the central property of dopamine 2 receptor antagonism and, in association with this property, can cause extrapyramidal side effects (EPS). Atypical antipsychotics are so-called because they generally have a lower propensity to cause EPS than the older agents; the exact reason for this is unknown but is believed to be due to the fact that these agents have the additional property of 5HT2A antagonism and/or dopa-mine 2 partial agonism (as opposed to antagonism).

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Anxiety and Depression 101

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