Phenylpropanolamine is an amphetamine derivative that has been used as a stimulant, decongestant, and anorectic agent. Its psychomotor stimulant effects are much weaker than those of ► amphetamine in humans. It has been widely used in cough and cold preparations. It has been withdrawn from several countries because of the risk of stroke. It has been subject to abuse in mixtures with other mild stimulants such as ► caffeine and ephedrine, with which it interacts to produce more powerful psychomotor activation.
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