Amobarbital is a medium- to long-acting sedative ► barbiturate medication used in the treatment of severe and refractory anxiety and insomnia. It is sometimes used in conjunction with ► antipsychotic medication in acute psychotic episodes. Unwanted effects include sedation, headaches, paradoxical excitement, confusion, cognitive and psychomotor impairment, and confusion in the elderly. Interaction with ► alcohol can be hazardous. It depresses respiration and is highly toxic in overdose. It can induce liver microsomal enzymes. Long-term use induces dependence with severe withdrawal reactions. Recreational use and abuse can occur: amobarbital is a scheduled substance.
Was this article helpful?