Drug Self Administration Definition

In the drug self-administration procedure, animal or human subjects perform an operant response (e.g., lever press, nose-poke) to receive abused drugs that serve as appetitive unconditioned stimuli, paralleling effects of palatable food, or other non-pharmacological rewards. The drug is often administered via a chronically indwelling venous catheter although other routes are also used (e.g., oral). The premise of these studies is that the drug rewards control behavior by functioning as a positive reinforcer. A stimulus is defined as a positive reinforcer if its presentation following a response increases or maintains the likelihood that the response will reoccur.

Cross-References

► Conditioned Place Preference

► Drug Dependence

► Self-Administration of Drugs

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