These are neurons with cell bodies located in sensory ganglia with processes terminating in the periphery (skin, viscera, other) and in the spinal cord in the CNS. They convey the first (primary) sensory information to the spinal cord. They vary in cell body size, axon diameter, conduction velocity, and their content of neurotransmit-ters and neuroactive peptides. These differences and the distribution of central and peripheral ends account for sensory modality content. Small-diameter primary sensory neurons might, in addition, liberate neuropeptides antidromically with pro-inflammatory consequences.
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