Synonyms

Cognitive deficit; Neurocognitive dysfunction Definition

Cognitive impairment is considered a core feature of schizophrenia that is related to the daily functioning of patients. On average, cognitive impairment in schizophrenia is severe to moderately severe compared with healthy controls. Cognitive impairment is not state-related and is not specific to subtypes of the illness. It includes problems in speed of processing, attention/vigilance, working memory, verbal learning, visual learning, reasoning and problem solving, and social cognition. These deficits can also serve as an endophenotype for the illness and are

Predicted action of D-cycloseririe 50 mg

Agonist property - potentiate low endogenous tone

Antagonist property - reduce high endogenous tone considered a reasonable treatment target in individuals with schizophrenia.

affecting the remaining processes, or that there are no interactions among the cognitive components of a task.

Cross-References

► Endophenotype

► Schizophrenia

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