SAMPLE ORIGIN SAMPLE PREP./SIZE PYROL. CONDITIONS TOTAL ION COUNTS
CHONDROITIN SULPHATE A, Na-salt poly[(l+4)£GlcAg(l-*3)l>GalNAcB]; O-sulphated at position 4 of GalNAc; see insert in spectrum
Seikagaku Kogyo Co. Ltd., Tokyo, Japan suspension in methanol; 10 ug standard
REMARKS - The relatively large difference between this spectrum and that of the 6-sulphate analogue (Spectrum A.17) is remarkable. Probably this difference is attributable to differences in the ionic state or purity of the samples (the above spectrum shows much fewer protein fragment peaks than Spectrum A.17) rather than to the difference in the position of the sulphate substituents. These differences are less pronounced in the spectra obtained from PBS suspensions of the compounds (Spectra A.17a, A.18a).
Was this article helpful?