SAMPLE ORIGIN SAMPLE PREP./SIZE PYROL. CONDITIONS TOTAL ION COUNTS
CHONDROITIN SULPHATE C, Na-salt poly[(1-+4)flG1cAg(1-»-3)l>Ga1NAcB]; O-sulphated at position 6 of GalNAc; see insert in spectrum
Seikagaku Kogyo Co. Ltd., Tokyo, Japan suspension in methanol; 10
REMARKS - As is to be expected, this spectrum resembles that of hyaluronic acid (Spectrum A.16). Peaks at m/z 96, 112 and 114 indicate the GlcA residues; the peaks at m/z 59 (acetamide) and 125 are indicative of the GalNAc residues. The signal at m/z 64 (S02+°) apparently represents the sulphate moieties, the relatively low intensity might be connected with the fact that the compound is analysed in the salt form. The presence of ion signals at m/z 34, 48, 76, 92, 94, 108 and 117 probably indicates proteinaceous contaminants. Compare also with Spectrum A.18, showing the 4-sulphated analogue.
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