Preventing Transition from Acute to Chronic Pain Use of Analgesics with Different Pharmacology

An intense nociceptive impulse transmitted to the dorsal horn of the spinal cord, always results in the release of excitatory neurotransmitters and peptides. Aside from activating interneuronal cells, they also stimulate the cells of the spinotha-lamic tract resulting in a prolonged sensitization and augmentation of all incoming further nociceptive impulses. Such an effect can outlast the original impulse [7], a phenomenon called central hypersensitization or "wind-up" [91, 92]. Clinically this is related to hyperalgesia in the damaged area accompanied by dysesthesia in the surrounded skin with prolonged pain [6, 69].

Peace in Pain

Peace in Pain

Free Your Mind And Achieve Peace. Discover How To Live In Peace And Harmony In A World Full Of Uncertainty And Dramatically Improve Your Quality Of Life Today. Finally You Can Fully Equip Yourself With These “Must Have” Tools For Achieving Peace And Calmness And Live A Life Of Comfort That You Deserve.

Get My Free Ebook


Post a comment