Info

Anatomy Event

Pain threshold

Figure 2.34 Changes in pain sensation induced by tissue injury: hyperalgesia and allodynia. Normal pain sensation occurs in response to pain stimuli. This dose-response curve is shifted to the left by the release of pain mediators from injured tissue. This causes hyperalgesia, that is, increased sensitivity to noxious stimuli and allodynia, that is, pain in response to stimuli that normally do not provoke pain. Drugs such as aspirin will shift the dose-response curve for pain backward to the right by peripheral and central modes of action. (modified after [358]).

Pain threshold

Figure 2.34 Changes in pain sensation induced by tissue injury: hyperalgesia and allodynia. Normal pain sensation occurs in response to pain stimuli. This dose-response curve is shifted to the left by the release of pain mediators from injured tissue. This causes hyperalgesia, that is, increased sensitivity to noxious stimuli and allodynia, that is, pain in response to stimuli that normally do not provoke pain. Drugs such as aspirin will shift the dose-response curve for pain backward to the right by peripheral and central modes of action. (modified after [358]).

Was this article helpful?

0 0

Post a comment