Summary

In summary, two members of this superfamily have been isolated and characterized. One of them, dEAATl, has properties very similar to those described for other known glutamate transporters, whereas the other appears to be a high-affinity aspartate transporter. Their expression profiles suggest that both these transporters have important functions in the nervous system. The restricted expression of dEAAT2 in the adult retina and lamina is particularly noteworthy, although no known functions for aspartate have been described in the Drosophila retina to date. No mutants have been isolated in either of the genes encoding these proteins, and functions of the proteins in vivo are unknown.

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