In the last third of the twentieth century, the R&D of diseases endemic in developing countries was, for the most part, neglected. However, in the first decade of the twenty-first century, the situation has started to change, as significant advances have been achieved in the science and funding commitment to the area. Hopefully, this should enable a flow of desperately needed new drugs to reach the market in the coming years. General research strategies for DDW drug discovery will be briefly outlined below and are covered in greater depth in the following chapters.
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