References

1. Hotez PJ, Fenwick A, Savioli L, Molyneux DH (2009) Lancet 373:1570-1575

2. Vanderelst D, Speybroeck N (2010) PLoS Negl Trop Dis 4(1):e576

3. Trouiller P, Olliaro P, Torreele E, Orbinski J, Laing R, Ford N (2002) Lancet 359:2188-2194

4. Matter A, Keller KH (2008) Drug Discovery Today 13(7/8):347-352

5. Mathers CD, Ezzati M, Lopez AD (2007) PLoS Negl Trop Dis 1(2):e114

6. King CH, Bertino AM (2008) PLoS Negl Trop Dis 2(3):e209

7. Conteh L, Engels T, Molyneux DH (2010) Lancet 375:239-247

8. Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL (2006) Global burden of disease and risk factors. Oxford University Press and The World Bank, New York

9. Molyneux DH (2008) Trans R Soc Trop Med Hyg 102(6):509-519

10. Boschi-Pinto C, Velebit L, Shibuya K (2008) Bull World Health Org 86(9):657-736

11. Mueller I, Galinski MR, Baird JK, Carlton JM, Kochar DK et al (2009) Lancet Infect Dis 9(9):555-566

12. Velayati AA, Farnia P, Masjedi MR, Ibrahim TA, Tabarsi P et al (2009) Eur Respir J 34(5):1202-1203

13. Velayati AA, Masjedi MR, FarniaP, Tabarsi P, Ghanavi J et al (2009) Chest 136(2):420-425

14. Brent AJ, Anderson ST, Kampmann B (2008) Trans R Soc Trop Med Hyg 102:217-218

15. Kyle JL, Harris E (2008) Annu Rev Microbiol 62:71-92

16. Halstead SB (2007) Lancet 370:1644-1652

17. Gould EA, Solomon T (2008) Lancet 371:500-509

18. Hotez PJ, Molyneux DH, Fenwick A, Ottesen E, Sachs SE et al (2006) PLoS Med 3(5):e102

19. Molyneux DH, Hotez PJ, Fenwick A (2005) PLoS Med 2(11):e336

20. Smits HL (2009) Expert Rev Anti Infect Ther 7(1):37-56

21. Hotez PJ, Molyneux DH, Fenwick A, Kumaresan J, Sachs SE et al (2007) N Engl J Med 357:1018-1027

22. Ameen M (2007) Expert Opin Pharmacother 8(16):2689-2699

23. Den Boer ML, Alvar J, Davidson RN, Ritmeijer K, Balasegaram M (2009) Expert Opin Emerg Drugs 14(3):395-410

24. Reithinger R, Dujardin JC, Louzir H, Pirmez C, Alexander B et al (2007) Lancet Infect Dis 7:581-596

25. Fevre EM, Wissmann BV, Welburn SC, Lutumba P (2008) PLoS Negl Trop Dis 2(12):e333

26. D'Silva C (2007) Drugs Future 32(2):149-160

27. Kennedy PGE (2008) Ann Neurol 64:116-127

28. Urbina JA, Docampo R (2003) Trends Parasitol 19(11):495-501

29. Von A, Zaragoza E, Jones D, Rodriguez-Morales AJ, Franco-Paredes C (2007) J Infect Dev Countries 1(2):99-111

30. Wells TNC, Alonso PL, Gutteridge WE (2009) Nat Rev Drug Discovery 8:879-891

31. Miller LH, Baruch DI, Marsh K, Doumbo OK (2002) Nature 415:673-679

32. Greenwood BM, Fidock DA, Kyle DE, Kappe SHI, Alonso PL et al (2008) J Clin Invest 118(4):1266-1276

33. Tarleton RL, Reithinger R, Urbina JA, Kitron U, Gurtler RE (2007) PLoS Med 4(12):e332

34. Tarleton RL (2001) Int J Parasitol 31(5-6):549-553

35. Muturi EJ, Jacob BG, Kim CH, Mbogo CM, Novak RJ (2008) Parasitol Res 102:175-181

36. Maher D, Harries A, Getahun H (2005) Trop Med Int Health 10:734-742

37. Van Eijk AM, Ayisi JG, ter Kuile FO, Misore AO, Otieno JA et al (2002) Am J Trop Med Hyg 67(1):44-53

38. Harms G, Feldmeier H (2005) Infect Dis Clin North Am 19(1):121-135

39. Druilhe P, Tall A, Sokhna C (2005) Trends Parasitol 21(8):359-362

40. Raso G, Luginbühl A, Adjoua CA, Tian-Bi NT, Silue KD et al (2004) Int J Epidemiol 33(5):1092-1102

41. Borkow G, Weisman Z, Leng Q, Stein M, Kalinkovich A, Wolday D, Bentwich Z (2001) Scand J Infect Dis 33(8):568-571

42. Elliott AM, Kyosiimire J, Quigley MA, Nakiyingi J, Watera C et al (2003) Trans R Soc Trop Med Hyg 97(4):477-480

43. Boraschi D, Alemayehu MA, Aseffa A, Chiodi F, Chisi J et al (2008) PLoS Negl Trop Dis 2(6):e255

44. Cavalli A, Bolognesi ML (2009) J Med Chem 52:7339-7359

45. Solomon AW, Nayagam S, Pasvol G (2009) Trans R Soc Trop Med Hyg 103:647-652

46. Duncan K (2003) Tuberculosis 83:201-207

47. Espinal MA (2003) Tuberculosis 83:44-51

48. Wright A, Zignol M, Van Deun A, Falzon D, Gerdes SR et al (2009) Lancet 373 (9678):1861-1873

49. Johnson R, Streicher EM, Louw GE, Warren RM (2009) Curr Issues Mol Biol 8:97-112

50. Aponte JJ, Schellenberg D, Egan A, Breckenridge A, Carneiro I et al (2009) Lancet 374 (9700):1533-1542

51. Ma Z, Lienhardt C, McIlleron H, Nunn AJ, Wang X (2010) Lancet 375:2100-2109. doi:10.1016/S0140-6736(10)60359-9

52. Mahoney RT, Krattiger A, Clemens JD, Curtiss R (2007) Vaccine 25:4003-4011

53. Trouiller P, Torreele E, Olliaro P, White N, Foster S et al (2001) Trop Med Int Health 6(11):945-951

54. Gallup JL, Sachs JD (2001) Am J Trop Med Hyg 64(1-2 Suppl):85-96

55. Sachs J, Malaney P (2002) Nature 415:680-685

56. Laxminarayan R, Klein E, Dye C, Floyd K, Darley S et al (2007) Economic benefit of tuberculosis control. The World Bank, Washington, DC

58. Caffrey CR, Steverding D (2008) Expert Opin Drug Discov 3(2):173-186

59. Nwaka S, Ridley RG (2003) Nat Rev Drug Discov 2(11):919-928

60. Nwaka S, Hudson A (2006) Nature Rev Drug Discov 5:941-955

61. Andrew Witty (2009) Harvard University, 13 February 2009

62. Gamo F-J, Sanz LM, Vidal J, de Cozar C, Alvarez E et al (2010) Nature 465:305-312

63. Kola I, Landis J (2004) Nature Rev Drug Discov 3:711-716

64. Villa S, Compagni A, Reich MR (2009) Int J Health Plann Manage 24(1):27-42

65. Ridley DB, Grabowski HG, Moe JL (2006) Health Affairs 25(2):313-324

66. Woodrow CJ, Krishna S (2006) Cell Mol Life Sci 63(14):1586-1596

67. Barnes KI, Watkins WM, White NJ (2008) Trends Parasitol 24(3):127-134

68. Kumari S, Ram VJ (2004) Drugs Today 40(6):487-500

69. Van den Boogaard J, Kibiki GS, Kisanga ER, Boeree MJ, Aarnoutse RE (2009) Antimicrob Agents Chemother 53(3):849-862

70. Croft SL, Sundar S, Fairlamb AH (2006) Clin Microbiol Rev 19(1):111-126

71. Barrett MP, Burchmore RJ, Stich A, Lazzari JO, Frasch AC et al (2003) Lancet 362 (9394):1469-1480

72. Perera M, Whitehead M, Molyneux D, Weerasooriya M, Gunatilleke G (2007) PLoS Negl Trop Dis 1(2):e128

73. Bockarie M, Taylor MJ, Gyapong JO (2009) Expert Rev Anti Infect Ther 7(5):595-605

74. Mathew N, Kalyanasundaram M (2007) Expert Opin Ther Patents 17(7):767-789

75. Molyneux DH, Bradley M, Hoerauf A, Kyelem D, Taylor MJ (2003) Trends Parasitol 19 (11):516-522

76. Van den Enden E (2009) Expert Opin Pharmacother 10(3):435-451

77. Newton PN, Green MD, Fernandez FM, Day NPJ, White NJ (2006) Lancet 6(9):602-613

78. Cockburn R, Newton PN, Agyarko EK, Akunyili D, White NJ (2005) PLoS Med 2(4):e100

79. Dondorp AM, Newton PN, Mayxay M, Van Damme W, Smithuis FM et al (2004) Trop Med Int Health 9(12):1241-1246

80. Newton PN, Fernandez FM, Plançon A, Mildenhall DC, Green MD et al (2008) PLoS Med 5(2):e32

81. Skeiky YAW, Sadoff JC (2006) Nat Rev Microbiol 4:469-476

82. Sacarlal J, Aide P, Aponte JJ, Renom M, Leach A et al (2009) J Infect Dis 200(3):329-336

83. Velazquez FR (2009) Pediatr Infect Dis J 28(3):S54-S56

84. Da'dara AA, Harn DA (2005) Expert Rev Vaccines 4(4):575-589

85. Crampton A, Vanniasinkam T (2007) Infect Genet Evolution 7(5):664-673

86. Hotez PJ, Brown AS (2009) Biologicals 37(3):160-164

87. WHO, UNICEF, World Bank (2009) State of the world's vaccines and immunization, 3rd edn. WHO, Geneva

88. Webster DP, Farrar J, Rowland-Jones S (2009) Lancet Infect Dis 9(11):678-687

89. Ernest TB, Elder DP, Martini LG, Roberts M, Ford JL (2007) J Pharm Pharmacol 59(8):1043-1055

90. Tolle MA (2009) Curr Probl Pediatr Adolesc Health Care 39(4):97-140

91. Billingsley PF, Foy B, Rasgon JL (2008) Trends Parasitol 24(9):396-400

92. Megy K, Hammond M, Lawson D, Bruggner RV, Birney E et al (2009) Infect Genet Evol 9:308-313

93. Alter HJ, Stramer SL, Dodd RY (2007) Semin Hematol 44(1):32-41

94. Dinnes J, Deeks J, Kunst H, Gibson A, Cummins E et al (2007) Health Technol Assess 11(3): 1-196

95. Blakemore R, Story E, Helb D, Kop J, Banada P et al (2010) J Clin Microbiol 48(7): 2495-2501. doi:10.1128/JCM.00128-10

96. Johnston KL, Taylor MJ (2007) Curr Infect Dis Rep 9(1):55-59

97. Hotez PJ (2009) Clin Pharmacol Ther 85(6):659-664

98. Ottesen EA, Hooper PJ, Bradley M, Biswas G (2008) PLoS Negl Trop Dis 2(10):e317

99. Bockarie M, Taylor MJ, Gyapong JO (2007) Expert Rev Anti Infect Ther 7(5):595-605

100. Udall DN (2007) Clin Infect Dis 44(1):53-60

101. Brooker S (2006) Trans R Soc Trop Med Hyg 101:1-8

102. Utzinger J, Raso G, Brooker S, De Savigny D, Tanner M et al (2009) Parasitol 136(13): 1859-1874

103. Castanys-Munoz E, Perez-Victoria JM, Gamarro F, Castanys S (2008) Antimicrob Agents Chemother 52(10):3573-3579

104. Basselin M, Denise H, Coombs GH, Barrett MP (2002) Antimicrob Agents Chemother 46 (12):3731-3738

105. Delespaux V, de Koning HP (2007) Drug Resist Updates 10(1-2):30-50

106. Wilkinson SR, Taylor MC, Horn D, Kelly JM, Cheeseman I (2008) Proc Natl Acad Sci U S A 105(13):5022-5027

107. White NJ (2004) J Clin Invest 113(8):1084-1092

108. Hyde JE (2005) Trends Parasitol 21(11):494-498

109. Mackinnon MJ (2005) Acta Trop 94(3):207-217

110. Shah NS, Wright A, Bai G-H, Barrera L, Boulahbal F et al (2007) Emerg Infect Dis 13(3): 380-387

111. Aziz MA, Wright A, Laszlo A, De Muynck A, Portaels F et al (2006) Lancet 368:2142-2154

112. Sibley CH, Philippe J, Guerin PJ, Ringwald P (2010) Trends Parasitol 26(5):221-224

113. Greenwood B, Alonso P, Ter Kuile FO, Hill J, Steketee RW (2007) Lancet Infect Dis 27:169-174

114. Broen K, Brustoski K, Engelmann I, Luty AJF (2007) Mol Biochem Parasitol 151:1-8

115. Rogerson SJ, Hviid L, Duffy PE, Leke RFG, Taylor DW (2007) Lancet Infect Dis 7:105-117

116. Aguas R, Lourenco JML, Gomes MGM, White LJ (2009) PLoS ONE 4(8):e6627

117. Hutton G, Schellenberg D, Tediosi F, Macete E, Kahigwa E et al (2009) Bull World Health Organ 87(2):123-129. doi:10.1590/S0042-96862009000200014

118. Gysels M, Pell C, Mathanga DP, Adongo P, Odhiambo F et al (2009) Malaria J 8:191. doi:10.1186/1475-2875-8-191

119. Moorthy VS, Reed Z, Smith PG (2009) Malaria J 8:23. doi:10.1186/1475-2875-8-23

120. Menendez C, Bardají A, Sigauque B, Sanz S, Aponte JJ et al (2010) PLoS ONE 5(2):e9438. doi:10.1371

121. Olliaro PL, Delenne H, Cisse M, Badiane M, Olliaro A et al (2008) Malaria J 7:234. doi:10.1186/1475-2875-7-234

122. O'Meara WP, Breman JG, McKenzieFE (2005) Malaria J4:33. doi:10.1186/1475-2875-4-33

123. Harrington WE, Mutabingwa TK, Muehlenbachs A, Sorensen B, Bolla MC et al (2009) PNAS 106(22):9027-9032

124. Chico RM, Pittrof R, Greenwood B, Chandramohan D (2008) Malaria J 7:255. doi:10.1186/ 1475-2875-7-255

125. White NJ, Pongtavornpinyo W (2003) Proc R Soc Lond B 270:545-554

126. DeRiemer K, García-García L, Bobadilla-del-Valle M, Palacios-Martínez M (2005) Lancet 365(9466):1239-1245

127. Payne DJ, Gwynn MN, Holmes DJ, Pompliano DL (2007) Nature Rev Drug Discov 6(1): 29-40

128. Chaudhary K, Roos D (2005) Nat Biotechnol 23(9):1089-1091

129. Winzeler EA (2006) Nat Rev Microbiol 4:145-151

130. Dharia NV, Chatterjee A, Winzeler EA (2010) Curr Opin Investig Drugs 11(2):131-138

131. Fairlamb AH, Cerami A (1992) Annu Rev Microbiol 46:695-729

132. Dias B, Marcio V, Ely F, Palma MS, de Azevedo WF et al (2007) Curr Drug Targets 8(3): 437-444

133. Oliveira JS, Vasconcelos IB, Moreira IS, Santos DS, Basso LA (2007) Curr Drug Targets 8(3):399-411

134. Cervantes S, Prudhomme J, Carter D, Gopi KG, Li Q (2009) BMC Cell Biol 10:45

135. Baniecki ML, Wirth DF, Clardy J (2007) Antinicrob Agents Chemother 51(2):716-723

136. Plouffe D, Brinker A, McNamara C, Henson K, Kato N et al (2008) PNAS 105(26): 9059-9064

137. Guiguemde WA, Shelat AA, Bouck D, Duffy S, Crowther GJ et al (2010) Nature 465(20): 311-315

138. Joachimiak MP, Chang C, Rosenthal PJ, Cohen FE (2001) Mol Med 7(10):698-710

139. Doerig C, Billker O, Haystead T, Sharma P, Tobin AB et al (2008) Trends Parasitol 24(12): 570-577

140. Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S et al (2009) J Med Chem 52(8): 2185-2187

141. Bermudez LE, Kolonoski P, Wu M, Aralar PA, Inderlied CB et al (1999) Antimicrob Agents Chemother 43(8):1870-1874

142. Danelishvili L, Wu M, Young LS, Bermudez LE (2005) Antimicrob Agents Chemother 49(9):3707-3714

143. Rossignol JF, Abu-Zekry M, Hussein A, Santoro MG (2006) Lancet 368(9530):124-129

144. Baldwin J, Michnoff CH, Malmquist NA, White J, Roth MG (2005) J Biol Chem 280(23): 21847-21853

145. Gujjar R, Marwaha A, El Mazouni F, White J, White KL et al (2009) J Med Chem 52(7): 1864-1872

146. Larson ET, Deng W, Krumm BE, Napuli A, Mueller N et al (2008) J Mol Biol 381(4): 975-988

147. Taylor Ringia EA, Schramm VL (2005) Curr Top Med Chem 5(13):1237-1258

148. Madrid DC, Ting LM, Waller KL, Schramm VL, Kim K (2008) J Biol Chem 283(51): 35899-35907

149. Olliaro P, Wells TN (2009) Clin Pharmacol Ther 85(6):584-595

150. Gardner MJ, Hall N, Fung E, White O, Berriman M et al (2002) Nature 419(6906):498-511

151. Carlton JM, Adams JH, Silva JC, Bidwell SL, Lorenzi H et al (2008) Nature 455(7214): 757-763

152. Pain A, Bohme U, Berry AE, Mungall K, Finn RD et al (2008) Nature 455:799-803

153. Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C et al (1998) Nature 393:537-544

154. Garnier T, Eiglmeier K, Camus JC, Medina N, Mansoor H et al (2003) PNAS 100(13): 7877-7882

155. Ivens AC, Peacock CS, Worthey EA, Murphy L, Aggarwal G et al (2005) Science 309 (5733):436-442

156. Peacock CS, Seeger K, Harris D, Murphy L, Ruiz JC et al (2007) Nat Genet 39(7):839-847

157. Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H et al (2005) Science 309 (5733):416-422

158. El-Sayed NM, Myler PJ, Bartholomeu DC, Nilsson D, Aggarwal G et al (2005) Science 309 (5733):409-415

159. Hu M, Chilton NB, Gasser RB (2002) Int J Parasitol 32(2):145-158

160. Ghedin E, Wang S, Spiro D, Caler E, Zhao Q et al (2007) Science 317(5845):1756-1760

161. Zhou Y, Zheng H, Chen Y, Zhang L, Wang K et al (2009) Nature 460(7253):345-351

162. Berriman M, Haas BJ, LoVerde PT, Wilson RA, Dillon GP et al (2009) Nature 460 (7253):352-358

163. Winzeler EA (2008) Nature 455:751-756

164. Hertz-Fowler C, Hall N (2004) Methods Mol Biol 270:45-74

165. Bahl A, Brunk B, Coppel RL, Crabtree J, Diskin SJ et al (2002) Nucleic Acids Res 30(1): 87-90

166. Saidani N, Grando D, Valadie H, Bastien O, Marechal E (2009) Infect Genet Evol 9(3): 359-367

167. Joubert F, Harrison CM, Koegelenberg RJ, Odendaal CJ, de Beer TAP (2009) Malaria J 8:178. doi:10.1186/1475-2875-8-178

168. Pethe K, Sequeira PC, Agarwalla S, Rhee K, Kuhen K et al (2010) Nat Commun 1(5):1-8

169. Fidock DA, Rosenthal PJ, Croft SL, Brun R, Nwaka S (2004) Nat Rev Drug Discov 3:509-520

170. Ito M, Kobayashi K, Nakahata T (2008) Curr Top Microbiol Immunol 324:53-76

171. Pearson T, Greiner DL, Shultz LD (2008) Curr Top Microbiol Immunol 324:25-51

172. Angulo-Barturen I, Jimenez-Diaz MB, Mulet T, Rullas J, Herreros E et al (2008) PLoS ONE 3(5):e2252

173. Jimenez-Diaz MB, Mulet T, Gomez V, Viera S, Alvarez A et al (2009) Cytometry A 75(3): 225-235

174. Galinski MR, Barnwell JW (2008) Malaria J 7(Suppl 1):S9. doi:10.1186/1475-2875-7-S1-S9

175. Apt A, Kramnik I (2009) Tuberculosis (Edinb) 89(3):195-198

176. Pichugin AV, Yan BS, Sloutsky A, Kobzik L, Kramnik I (2009) Am J Pathol 174(6): 2190-2201

177. Doerig C, Meijer L (2007) Expert Opin Ther Targets 11(3):279-290

178. Geyer JA, Prigge ST, Waters NC (2005) Biochim Biophys Acta 1754(1-2):160-170

179. Nwaka S, Ramirez B, Brun R, Maes L, Douglas F et al (2009) PLoS Negl Trop Dis 3(8):e440

180. Olliaro P, Smith PG (2004) J HIV Ther 9(3):53-56

Top Med Chem 7: 47-124 DOI: 10.1007/7355_2011_13 © Springer-Verlag Berlin Heidelberg 2011 Published online: 29 April 2011

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