Acknowledgements

This work was performed as part of the RELIMO-project, which is funded by the German Federal Ministry for Education, Science, Research, and Technology (BMBF) under grant No. 0311623.

The authors are grateful to Dr Matthias Rarey from GMD-SCAI for kindly providing us with the Feature Tree distance matrix and for many valuable discussions. In addition, we would like to thank Dr Christian Lemmen from Combichem for making us familiar with the FlexS program.

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Perspectives in Drug Discovery and Design, 20: 245-264, 2000. KLUWER/ESCOM

© 2000 Kluwer Academic Publishers. Printed in the Netherlands.

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